Pharmaceutical industry-technical solutions for ultrapure water treatment equipment for pharmaceuticals

Requirements for process water

The process water of pharmaceutical manufacturers mainly refers to the water used in the process of washing bottles, ingredients and other processes in the production of preparations, as well as the water used in the process of refining and washing in the production of raw materials. The name of water should not be related to the water manufacturing process, such as deionized water, demineralized water, distilled water, that is, the water manufacturing process is decoupled from its name, but water is classified according to quality indicators from the perspective of chemistry and microorganisms

Water for injection is generally prepared from purified water by distillation (also reverse osmosis and ultrafiltration), with a chemical purity of up to 99.999% and no pyrogen. Since the preparation process of pure steam is the same as the process of preparing water for injection with distilled water, the same multi-effect distilled water machine or a separate pure steam generator can be used, so pure steam will be discussed together with water for injection.

Purified water process

Raw water → raw water booster pump → multi-media filter → activated carbon filter → water softener → precision filter → first-stage reverse osmosis → PH adjustment device → intermediate water tank → second-stage reverse osmosis → purified water tank → delivery pump → ultraviolet Sterilizer → microporous filter → water point (recommended process)

Raw water → raw water booster pump → multi-media filter → activated carbon filter → water softener → precision filter → first-stage reverse osmosis → intermediate water tank → intermediate water pump → ion exchange equipment → purified water tank → delivery pump → ultraviolet sterilizer → Microporous filter → water point (traditional process)

Raw water → raw water booster pump → multi-media filter → activated carbon filter → water softener → precision filter → first-stage reverse osmosis → intermediate water tank → intermediate water pump → EDI equipment → purified water tank → transfer pump → ultraviolet sterilizer → micro Hole filter → water point (the latest technology)

Purified water standard

Reference to water requirements for pharmaceutical production Reference to purified water standards Reference to purified water testing methods

Definition of secondary reverse osmosis:

The secondary reverse osmosis is to use the water produced by the primary reverse osmosis as the raw water for the second reverse osmosis purification, and the conductivity of the product water is ≤3μs/cm. It has been widely used in drinking pure water. Reverse osmosis technology is often used in pre-demineralization treatment, which can reduce the load of ion exchange resin by more than 90%, and the amount of resin regeneration agent can also be reduced by 90%. Therefore, it not only saves operating costs, but also contributes to environmental protection. The unique water treatment technology of reverse osmosis is beyond the reach of other water purification methods such as distillation, electrodialysis, and ion exchange.

Application tips:

  1. Preparation of sterile, heat-free purified water for the pharmaceutical industry;
  2. Biomedical water;
  3. Water for medical hemodialysis;
  4. Preparation of pure drinking water and beverage water;
  5. Pretreatment system for high-purity water used in the electronics industry;
  6. Preparation of boiler make-up water;
  7. Water for cosmetic ingredients;
  8. Pure water for liquor blending and pure water for beer production.
Water Treatment and Reverse Osmosis Systems of Hospital

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